Calcium Glycerophosphate BP
Calcium glycerophosphate is a Calcium salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate.
Calcium Glycerophosphate present in dental or oral hygiene products (toothpaste and mouthwash) due to its cariostatic effects. It is suggested that calcium glycerophosphate promotes plaque-pH buffering, elevation of plaque Calcium and phosphate levels and direct interaction with dental mineral. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings, and fillings. Other applications are in Animal Health, Cosmetics, Food & Beverage, and Sports Nutrition Vitamins & Minerals.
Molecular Formula: C3H7CaO6P
Molecular Weight: 210.1 g/mol
CAS No.: 27214-00-2
|Character||It occurs as a white or almost white powder, hygroscopic.|
(a)Specified Test. The filter paper develops a blue color in contact with piperidine R.
(b)Specified Test. The filtrate gives reaction of phosphates.
(c) It gives reaction of calcium
|Solubility||Sparingly soluble in water, practically insoluble in ethanol (96%)|
|Appearance of solution||Solution is not more opalescent than reference suspension III.|
|Acidity or alkalinity||To 100 mL of solution S add 0.1 mL of phenolphthalein solution R. Not more than 1.5 mL of0.1 M hydrochloric acid or 0.5 mL of 0.1 M sodium hydroxide is required to change the color of the indicator.|
|Citric acid||Specified Test. No precipitate is formed.|
|Glycerol and ethanol (96%) soluble substances||Not more than 0.5%|
|Chlorides||Not more than 500 ppm|
|Phosphates||Not more than 400 ppm|
|Sulfate||Not more than 0.1%|
|Arsenic||Not more than 3 ppm|
|Iron||Not more than 50 ppm|
|Heavy Metals||Not more than 20 ppm|
|Loss on drying||Not more than 12.0%|
|Assay||Not less than 18.6% and not more than 19.4 % of Ca (dried substance).|
Shelf life, Storage and Packing
It should be stored in a segregated area in a cool and ventilated place away from combustible materials. Keep in a tightly closed container, sealed until ready for use. It is packed in 25kg or 50kg HDPE bags or drums as required.
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We observe WHO Good manufacturing practice and Good laboratory practice.